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Addition of a Viral Immunomodulatory Domain to Etanercept Generates a Bifunctional Chemokine and TNF Inhibitor

The inhibition of tumor necrosis factor (TNF) through the use of either antibodies or soluble receptors is a highly effective strategy for the clinical control of chronic inflammatory conditions such as rheumatoid arthritis. Different viruses have similarly exploited this concept by expressing a set...

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Detalhes bibliográficos
Publicado no:J Clin Med
Main Authors: Alejo, Alí, Sánchez, Carolina, Amu, Sylvie, Fallon, Padraic G., Alcamí, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7020083/
https://ncbi.nlm.nih.gov/pubmed/31877657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm9010025
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