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Bone Marrow-Derived Mesenchymal Stromal Cells: A Novel Target to Optimize Hematopoietic Stem Cell Transplantation Protocols in Hematological Malignancies and Rare Genetic Disorders

Mesenchymal stromal cells (MSCs) are crucial elements in the bone marrow (BM) niche where they provide physical support and secrete soluble factors to control and maintain hematopoietic stem progenitor cells (HSPCs). Given their role in the BM niche and HSPC support, MSCs have been employed in the c...

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Detalhes bibliográficos
Publicado no:J Clin Med
Main Authors: Crippa, Stefania, Santi, Ludovica, Bosotti, Roberto, Porro, Giulia, Bernardo, Maria Ester
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7019991/
https://ncbi.nlm.nih.gov/pubmed/31861268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm9010002
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