Phase I Study of a B Cell-Based and Monocyte-Based Immunotherapeutic Vaccine, BVAC-C in Human Papillomavirus Type 16- or 18-Positive Recurrent Cervical Cancer

BVAC-C is a B cell-based and monocyte-based immuno-therapeutic vaccine transfected with a recombinant human papillomavirus (HPV) 16/18 E6/E7 gene and loaded with alpha-galactosyl ceramide, which is a natural killer T cell ligand. This phase I study sought to determine the tolerability and immunogeni...

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Publié dans:J Clin Med
Auteurs principaux: Choi, Chel Hun, Choi, Hyun Jin, Lee, Jeong-Won, Kang, Eun-Suk, Cho, Duck, Park, Byung Kwan, Kim, Yong-Man, Kim, Dae-Yeon, Seo, Hyungseok, Park, Myunghwan, Kim, Wuhyun, Choi, Ki-Young, Oh, Taegwon, Kang, Chang-Yuil, Kim, Byoung-Gie
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7019768/
https://ncbi.nlm.nih.gov/pubmed/31948126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm9010147
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