NOTCH4 maintains quiescent mesenchymal-like breast cancer stem cells via transcriptionally activating SLUG and GAS1 in triple-negative breast cancer

Rationale: NOTCH4 receptor has been implicated in triple-negative breast cancer (TNBC) development and breast cancer stem cell (BCSC) regulation. However, the potential of NOTCH4 as a BCSC marker and the underlying mechanisms remain unclear. Methods: In this study, we determined the expression and a...

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Udgivet i:Theranostics
Main Authors: Zhou, Lei, Wang, Dong, Sheng, Dandan, Xu, Jiahui, Chen, Weilong, Qin, Yuanyuan, Du, Ruikai, Yang, Xiaoli, He, Xueyan, Xie, Ni, Liu, Suling, Zhang, Lixing
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2020
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7019177/
https://ncbi.nlm.nih.gov/pubmed/32104513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.38875
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