טוען...

Ranitidine and finasteride inhibit the synthesis and release of trimethylamine N-oxide and mitigates its cardiovascular and renal damage through modulating gut microbiota

Trimethylamine N-oxide (TMAO) leads to the development of cardiovascular and chronic kidney diseases, but there are currently no potent drugs that inhibit the production or toxicity of TMAO. In this study, high-fat diet-fed ApoE-/- mice were treated with finasteride, ranitidine, and andrioe. Subsequ...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Int J Biol Sci
Main Authors: Liu, Junfeng, Lai, Lingyun, Lin, Jiajia, Zheng, Jiajia, Nie, Xiaoli, Zhu, Xiaoye, Xue, Jun, Liu, Te
פורמט: Artigo
שפה:Inglês
יצא לאור: Ivyspring International Publisher 2020
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7019130/
https://ncbi.nlm.nih.gov/pubmed/32071549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.40934
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