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Opposite Charge Movements Within the Photoactive Site Modulate Two-Step Channel Closing in GtACR1
Guillardia theta anion channelrhodopsin 1 is a light-gated anion channel widely used as an optogenetic inhibitory tool. Our recently published crystal structure of its dark (closed) state revealed that the photoactive retinylidene chromophore is located midmembrane in a full-length intramolecular tu...
Shranjeno v:
| izdano v: | Biophys J |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Biophysical Society
2019
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7018983/ https://ncbi.nlm.nih.gov/pubmed/31676131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.10.009 |
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