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Allele-specific miRNA-binding analysis identifies candidate target genes for breast cancer risk

Most breast cancer (BC) risk-associated single-nucleotide polymorphisms (raSNPs) identified in genome-wide association studies (GWAS) are believed to cis-regulate the expression of genes. We hypothesise that cis-regulatory variants contributing to disease risk may be affecting microRNA (miRNA) genes...

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Détails bibliographiques
Publié dans:NPJ Genom Med
Auteurs principaux: Jacinta-Fernandes, Ana, Xavier, Joana M., Magno, Ramiro, Lage, Joel G., Maia, Ana-Teresa
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7018948/
https://ncbi.nlm.nih.gov/pubmed/32128252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41525-019-0112-9
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