PERK-mediated expression of peptidylglycine α-amidating monooxygenase supports angiogenesis in glioblastoma

PKR-like kinase (PERK) plays a significant role in inducing angiogenesis in various cancer types including glioblastoma. By proteomics analysis of the conditioned medium from a glioblastoma cell line treated with a PERK inhibitor, we showed that peptidylglycine α-amidating monooxygenase (PAM) expres...

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Pubblicato in:Oncogenesis
Autori principali: Soni, Himanshu, Bode, Julia, Nguyen, Chi D. L., Puccio, Laura, Neßling, Michelle, Piro, Rosario M., Bub, Jonas, Phillips, Emma, Ahrends, Robert, Eipper, Betty A., Tews, Björn, Goidts, Violaine
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7018722/
https://ncbi.nlm.nih.gov/pubmed/32054826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-020-0201-8
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