Overexpression of Galectin 3 in Pancreatic β Cells Amplifies β-Cell Apoptosis and Islet Inflammation in Type-2 Diabetes in Mice

Aims/Hypothesis: Galectin 3 appears to play a proinflammatory role in several inflammatory and autoimmune diseases. Also, there is evidence that galectin 3 plays a role in both type-1 and type-2 diabetes. During obesity, hematopoietic cell-derived galectin 3 induces insulin resistance. While the rol...

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Detalles Bibliográficos
Publicado en:Front Endocrinol (Lausanne)
Main Authors: Petrovic, Ivica, Pejnovic, Nada, Ljujic, Biljana, Pavlovic, Sladjana, Miletic Kovacevic, Marina, Jeftic, Ilija, Djukic, Aleksandar, Draginic, Nevena, Andjic, Marijana, Arsenijevic, Nebojsa, Lukic, Miodrag L., Jovicic, Nemanja
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
Assuntos:
Endocrinology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7018709/
https://ncbi.nlm.nih.gov/pubmed/32117058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2020.00030
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