Combining copy number, methylation markers, and mutations as a panel for endometrial cancer detection via intravaginal tampon collection

OBJECTIVE: We aimed to assess whether endometrial cancer (EC) can be detected in shed DNA collected with vaginal tampon by analyzing copy number, methylation markers, and mutations. METHODS: Tampons were collected prior to hysterectomy from 38 EC patients and 28 women with benign indications. Extrac...

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Vydáno v:Gynecol Oncol
Hlavní autoři: Sangtani, Ajleeta, Wang, Chen, Weaver, Amy, Hoppman, Nicole L., Kerr, Sarah E., Abyzov, Alexej, Shridhar, Viji, Staub, Julie, Kocher, Jean-Pierre A., Voss, Jesse S., Podratz, Karl C., Wentzensen, Nicolas, Kisiel, John B., Sherman, Mark E., Bakkum-Gamez, Jamie N.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7018609/
https://ncbi.nlm.nih.gov/pubmed/31787246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2019.11.028
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