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Nodal β spectrins are required to maintain Na(+) channel clustering and axon integrity
Clustered ion channels at nodes of Ranvier are critical for fast action potential propagation in myelinated axons. Axon-glia interactions converge on ankyrin and spectrin cytoskeletal proteins to cluster nodal Na(+) channels during development. However, how nodal ion channel clusters are maintained...
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| Pubblicato in: | eLife |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
eLife Sciences Publications, Ltd
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7018506/ https://ncbi.nlm.nih.gov/pubmed/32052742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.52378 |
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