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Brief Report: SWOG S1400B (), A Phase II Study of GDC-0032 (Taselisib) for Previously Treated PI3K-Positive Patients with Stage IV Squamous Cell Lung Cancer (Lung-MAP Sub-Study)

BACKGROUND: S1400B is a biomarker-driven Lung-MAP sub-study evaluating the phosphatidylinositide 3-kinase (PI3K) inhibitor taselisib (GDC-0032) in patients with PI3K pathway-activated squamous NSCLC (SqNSCLC). METHODS: Eligible patients had tumoral PIK3CA alterations by next generation sequencing an...

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發表在:J Thorac Oncol
Main Authors: Langer, Corey J., Redman, Mary W., Wade, James L., Aggarwal, Charu, Bradley, Jeffrey D., Crawford, Jeffrey, Stella, Philip J., Knapp, Mark H., Miao, Jieling, Minichiello, Katherine, Herbst, Roy S., Kelly, Karen, Gandara, David R., Papadimitrakopoulou, Vassiliki A.
格式: Artigo
語言:Inglês
出版: 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017958/
https://ncbi.nlm.nih.gov/pubmed/31158500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtho.2019.05.029
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