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ITGAV targeting as a therapeutic approach for treatment of metastatic breast cancer
During tumorigenesis and metastasis, integrins regulate localization and activity of proteolytic enzymes that remodel the extracellular matrix. Previous studies have demonstrated blocking of α(V)β(3) to effectively inhibit proliferation, angiogenesis, and the survival of various cancer cell types. H...
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| Gepubliceerd in: | Am J Cancer Res |
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| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
e-Century Publishing Corporation
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7017729/ https://ncbi.nlm.nih.gov/pubmed/32064162 |
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