Hepatitis B virus X protein promotes tumor invasion and poor prognosis in hepatocellular carcinoma via phosphorylation of paxillin at Serine 178 by activation of the c-Jun NH2-terminal kinase

Hepatitis B virus X protein (HBx) plays critical roles in hepatocellular tumorigenesis by activating different signaling pathways, including the c-Jun NH2-terminal kinase (JNK) pathway. Phosphorylation of paxillin (PXN) promotes cell migration via activation of the JNK signaling pathway, but PXN ove...

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Detalhes bibliográficos
Publicado no:Am J Cancer Res
Main Authors: Chen, Ming-Jenn, Wu, De-Wei, Shen, Ching-Ju, Cheng, Ya-Min, Wu, Cheng-Chung, Lee, Huei
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017728/
https://ncbi.nlm.nih.gov/pubmed/32064167
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