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A Novel Mass Spectrometry Platform for Multiplexed N-glycoprotein Biomarker Discovery from Patient Biofluids by Antibody Panel Based N-glycan Imaging

A new platform for N-glycoprotein analysis from serum that combines matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI MSI) workflows with antibody slide arrays is described. Antibody Panel Based (APB) N-glycan imaging allows for the specific capture of N-glycoproteins by a...

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Detalhes bibliográficos
Publicado no:Anal Chem
Main Authors: Black, Alyson P., Liang, Hongyan, West, Connor A., Wang, Mengjun, Herrera, Harmin P., Haab, Brian B., Angel, Peggi M., Drake, Richard R., Mehta, Anand S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017646/
https://ncbi.nlm.nih.gov/pubmed/31177770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.9b01445
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