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Reliability and correlation of mixture cell correction in methylomic and transcriptomic blood data

OBJECTIVES: The number of DNA methylome and RNA transcriptome studies is growing, but investigators have to consider the cell type composition of tissues used. In blood samples, the data reflect the picture of a mixture of different cells. Specialized algorithms can address the cell-type heterogenei...

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Bibliografiske detaljer
Udgivet i:BMC Res Notes
Main Authors: Chaumette, Boris, Kebir, Oussama, Dion, Patrick A., Rouleau, Guy A., Krebs, Marie-Odile
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017605/
https://ncbi.nlm.nih.gov/pubmed/32051015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13104-020-4936-2
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