Targeted Nano-Drug Delivery of Colchicine against Colon Cancer Cells by Means of Mesoporous Silica Nanoparticles

Antimitotics are important anticancer agents and include the natural alkaloid prodrug colchicine (COL). However, a major challenge of using COL as an anticancer drug is its cytotoxicity. We developed a novel drug delivery system (DDS) for COL using mesoporous silica nanoparticles (MSNs). The MSNs we...

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Veröffentlicht in:Cancers (Basel)
Hauptverfasser: AbouAitah, Khaled, Hassan, Heba A., Swiderska-Sroda, Anna, Gohar, Lamiaa, Shaker, Olfat G., Wojnarowicz, Jacek, Opalinska, Agnieszka, Smalc-Koziorowska, Julita, Gierlotka, Stanislaw, Lojkowski, Witold
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017376/
https://ncbi.nlm.nih.gov/pubmed/31936103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12010144
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