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Glucose Uptake Stimulatory and PTP1B Inhibitory Activities of Pimarane Diterpenes from Orthosiphon stamineus Benth

Seven pimarane diterpenes (1–7) were isolated from Orthosiphon stamineus Benth. by assay-guided isolation. All of the isolates possessed a 2-deoxy-2-((7-nitro-2,1,3-benzoxadiazol-4-yl)amino)-d-glucose uptake effect in 3T3-L1 adipocytes at concentrations of 5 and 10 μM. Most of them showed potent inh...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Nguyen, Phi Hung, Tuan, Huynh Nhu, Hoang, Duc Thuan, Vu, Quoc Trung, Pham, Minh Quan, Tran, Manh Hung, To, Dao Cuong
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017366/
https://ncbi.nlm.nih.gov/pubmed/31835878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9120859
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