MGL1 Receptor Plays a Key Role in the Control of T. cruzi Infection by Increasing Macrophage Activation through Modulation of ERK1/2, c-Jun, NF-κB and NLRP3 Pathways

Macrophage galactose-C type lectin (MGL)1 receptor is involved in the recognition of Trypanosoma cruzi (T. cruzi) parasites and is important for the modulation of the innate and adaptive immune responses. However, the mechanism by which MGL1 promotes resistance to T. cruzi remains unclear. Here, we...

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Veröffentlicht in:Cells
Hauptverfasser: Rodriguez, Tonathiu, Pacheco-Fernández, Thalia, Vázquez-Mendoza, Alicia, Nieto-Yañez, Oscar, Juárez-Avelar, Imelda, Reyes, José L., Terrazas, Luis I., Rodriguez-Sosa, Miriam
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017267/
https://ncbi.nlm.nih.gov/pubmed/31906385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9010108
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