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Heat Shock Protein 90 Chaperone Regulates the E3 Ubiquitin-Ligase Hakai Protein Stability

The E3 ubiquitin-ligase Hakai binds to several tyrosine-phosphorylated Src substrates, including the hallmark of the epithelial-to-mesenchymal transition E-cadherin, and signals for degradation of its specific targets. Hakai is highly expressed in several human cancers, including colon cancer, and i...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancers (Basel)
Prif Awduron: Díaz-Díaz, Andrea, Roca-Lema, Daniel, Casas-Pais, Alba, Romay, Gabriela, Colombo, Giovanni, Concha, Ángel, Graña, Begoña, Figueroa, Angélica
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017148/
https://ncbi.nlm.nih.gov/pubmed/31952268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12010215
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