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Epigenetic Silencing of Ubiquitin Specific Protease 4 by Snail1 Contributes to Macrophage-Dependent Inflammation and Therapeutic Resistance in Lung Cancer

There is a positive feedback loop driving tumorigenesis and tumor growth through coordinated regulation of epigenetics, inflammation, and stemness. Nevertheless, the molecular mechanism linking these processes is not well understood. In this study, we analyzed the correlation of de-ubiquitinases (DU...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Lai, Chao-Yang, Yeh, Da-Wei, Lu, Chih-Hao, Liu, Yi-Ling, Chuang, Yu-Chen, Ruan, Jhen-Wei, Kao, Cheng-Yuan, Huang, Li-Rung, Chuang, Tsung-Hsien
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016945/
https://ncbi.nlm.nih.gov/pubmed/31936290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12010148
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