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Transmission of Functional, Wild-Type Mitochondria and the Fittest mtDNA to the Next Generation: Bottleneck Phenomenon, Balbiani Body, and Mitophagy

The most important role of mitochondria is to supply cells with metabolic energy in the form of adenosine triphosphate (ATP). As synthesis of ATP molecules is accompanied by the generation of reactive oxygen species (ROS), mitochondrial DNA (mtDNA) is highly vulnerable to impairment and, consequentl...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Tworzydlo, Waclaw, Sekula, Malgorzata, Bilinski, Szczepan M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016935/
https://ncbi.nlm.nih.gov/pubmed/31963356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes11010104
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