Ex-Vivo Treatment of Tumor Tissue Slices as a Predictive Preclinical Method to Evaluate Targeted Therapies for Patients with Renal Carcinoma

Clear cell renal cell carcinoma (ccRCC) is the third type of urologic cancer. At time of diagnosis, 30% of cases are metastatic with no effect of chemotherapy or radiotherapy. Current targeted therapies lead to a high rate of relapse and resistance after a short-term response. Thus, a major hurdle i...

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Vydáno v:Cancers (Basel)
Hlavní autoři: Roelants, Caroline, Pillet, Catherine, Franquet, Quentin, Sarrazin, Clément, Peilleron, Nicolas, Giacosa, Sofia, Guyon, Laurent, Fontanell, Amina, Fiard, Gaëlle, Long, Jean-Alexandre, Descotes, Jean-Luc, Cochet, Claude, Filhol, Odile
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016787/
https://ncbi.nlm.nih.gov/pubmed/31963500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12010232
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