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CD276-Positive Circulating Endothelial Cells Do Not Predict Response to Systemic Therapy in Advanced Colorectal Cancer

CD276 can discriminate between tumor derived and normal CECs (circulating endothelial cells). We evaluated whether CD276(+)CEC is a clinically relevant biomarker to predict response to palliative systemic therapy in patients with metastatic colorectal cancer (mCRC). Samples were prospectively collec...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cells
Hauptverfasser: Gootjes, Elske C., Kraan, Jaco, Buffart, Tineke E., Bakkerus, Lotte, Zonderhuis, Barbara M., Verhoef, Cornelis, Verheul, Henk M.W., Sleijfer, Stefan
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016770/
https://ncbi.nlm.nih.gov/pubmed/31948091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9010124
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