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Human and Mouse TRPA1 Are Heat and Cold Sensors Differentially Tuned by Voltage

Transient receptor potential ankyrin 1 channel (TRPA1) serves as a key sensor for reactive electrophilic compounds across all species. Its sensitivity to temperature, however, differs among species, a variability that has been attributed to an evolutionary divergence. Mouse TRPA1 was implicated in n...

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Bibliographic Details
Published in:Cells
Main Authors: Sinica, Viktor, Zimova, Lucie, Barvikova, Kristyna, Macikova, Lucie, Barvik, Ivan, Vlachova, Viktorie
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016720/
https://ncbi.nlm.nih.gov/pubmed/31878344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9010057
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