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Nicotine Induces Polyspermy in Sea Urchin Eggs through a Non-Cholinergic Pathway Modulating Actin Dynamics

While alkaloids often exert unique pharmacological effects on animal cells, exposure of sea urchin eggs to nicotine causes polyspermy at fertilization in a dose-dependent manner. Here, we studied molecular mechanisms underlying the phenomenon. Although nicotine is an agonist of ionotropic acetylchol...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Limatola, Nunzia, Vasilev, Filip, Santella, Luigia, Chun, Jong Tai
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016604/
https://ncbi.nlm.nih.gov/pubmed/31881774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9010063
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