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Nanoparticles Loaded with the BET Inhibitor JQ1 Block the Growth of Triple Negative Breast Cancer Cells In Vitro and In Vivo

Inhibition of bromo-and extra-terminal domain (BET) proteins, epigenetic regulators of genes involved in cell viability, has been efficiently tested in preclinical models of triple negative breast cancer (TNBC). However, the use of the selective BET-inhibitor JQ1 on humans is limited by its very sho...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Maggisano, Valentina, Celano, Marilena, Malivindi, Rocco, Barone, Ines, Cosco, Donato, Mio, Catia, Mignogna, Chiara, Panza, Salvatore, Damante, Giuseppe, Fresta, Massimo, Andò, Sebastiano, Russo, Diego, Catalano, Stefania, Bulotta, Stefania
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016573/
https://ncbi.nlm.nih.gov/pubmed/31905936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12010091
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