Nanoparticles Loaded with the BET Inhibitor JQ1 Block the Growth of Triple Negative Breast Cancer Cells In Vitro and In Vivo

Inhibition of bromo-and extra-terminal domain (BET) proteins, epigenetic regulators of genes involved in cell viability, has been efficiently tested in preclinical models of triple negative breast cancer (TNBC). However, the use of the selective BET-inhibitor JQ1 on humans is limited by its very sho...

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Dettagli Bibliografici
Pubblicato in:Cancers (Basel)
Autori principali: Maggisano, Valentina, Celano, Marilena, Malivindi, Rocco, Barone, Ines, Cosco, Donato, Mio, Catia, Mignogna, Chiara, Panza, Salvatore, Damante, Giuseppe, Fresta, Massimo, Andò, Sebastiano, Russo, Diego, Catalano, Stefania, Bulotta, Stefania
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016573/
https://ncbi.nlm.nih.gov/pubmed/31905936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12010091
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