Serial Xenotransplantation in NSG Mice Promotes a Hybrid Epithelial/Mesenchymal Gene Expression Signature and Stemness in Rhabdomyosarcoma Cells

Serial xenotransplantation of sorted cancer cells in immunodeficient mice remains the most complex test of cancer stem cell (CSC) phenotype. However, we have demonstrated in various sarcomas that putative CSC surface markers fail to identify CSCs, thereby impeding the isolation of CSCs for subsequen...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Skoda, Jan, Neradil, Jakub, Staniczkova Zambo, Iva, Nunukova, Alena, Macsek, Peter, Borankova, Karolina, Dobrotkova, Viera, Nemec, Pavel, Sterba, Jaroslav, Veselska, Renata
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016569/
https://ncbi.nlm.nih.gov/pubmed/31941033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12010196
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