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RNA-Based Therapeutics: From Antisense Oligonucleotides to miRNAs

The first therapeutic nucleic acid, a DNA oligonucleotide, was approved for clinical use in 1998. Twenty years later, in 2018, the first therapeutic RNA-based oligonucleotide was United States Food and Drug Administration (FDA) approved. This promises to be a rapidly expanding market, as many emergi...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cells
Auteurs principaux: Bajan, Sarah, Hutvagner, Gyorgy
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016530/
https://ncbi.nlm.nih.gov/pubmed/31936122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9010137
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