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Peptides of major basic protein and eosinophil cationic protein activate human mast cells

The eosinophil granule proteins, major basic protein (MBP) and eosinophil cationic protein (ECP), activate mast cells during inflammation; however the mechanism responsible for this activity is poorly understood. We found that some theoretical tryptase-digested fragments of MBP and ECP induced degra...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Rep
Main Authors: Ogasawara, Hiroyuki, Furuno, Masahiro, Edamura, Koji, Noguchi, Masato
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016281/
https://ncbi.nlm.nih.gov/pubmed/32072023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2019.100719
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