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The double-edged sword of cancer mutations: exploiting neoepitopes for the fight against cancer

Defects in DNA repair have been linked to the accumulation of somatic mutations in tumours. These mutations can promote oncogenesis; however, recent developments have indicated that they may also lead to a targeted immune response against the tumour. This response is initiated by the development of...

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Bibliographic Details
Published in:Mutagenesis
Main Authors: Alvarado-Cruz, Isabel, Meas, Rithy, Paluri, Sesha Lakshmi Arathi, Carufe, Kelly Estelle Wheeler, Khan, Mohammed, Sweasy, Joann Balazs
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016206/
https://ncbi.nlm.nih.gov/pubmed/31880305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/mutage/gez049
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