Characterization of HIV-1 diversity in various compartments at the time of primary infection by ultradeep sequencing

We used next-generation sequencing to evaluate the quantity and genetic diversity of the HIV envelope gene in various compartments in eight patients with acute infection. Plasma (PL) and seminal fluid (SF) were available for all patients, whole blood (WB) for seven, non-spermatozoid cells (NSC) for...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gaube, Géraldine, Armero, Alix, Salmona, Maud, Néré, Marie-Laure, Mahjoub, Nadia, Lascoux-Combe, Caroline, Gabassi, Audrey, Gallien, Sébastien, Amara, Ali, Molina, Jean Michel, Delaugerre, Constance, Chaix, Marie-Laure
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016127/
https://ncbi.nlm.nih.gov/pubmed/32051463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-59234-6
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