Novel Mutation Hotspots within Non-Coding Regulatory Regions of the Chronic Lymphocytic Leukemia Genome

Mutations in non-coding DNA regions are increasingly recognized as cancer drivers. These mutations can modify gene expression in cis or by inducing high-order chormatin structure modifications with long-range effects. Previous analysis reported the detection of recurrent and functional non-coding DN...

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Vydáno v:Sci Rep
Hlavní autoři: Mosquera Orgueira, Adrián, Rodríguez Antelo, Beatriz, Díaz Arias, José Ángel, Díaz Varela, Nicolás, Alonso Vence, Natalia, González Pérez, Marta Sonia, Bello López, José Luis
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7015923/
https://ncbi.nlm.nih.gov/pubmed/32051441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-59243-5
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