A Targeted Quantitative Proteomic Method Revealed a Substantial Reprogramming of Kinome during Melanoma Metastasis

Kinases are involved in numerous critical cell signaling processes, and dysregulation in kinase signaling is implicated in many types of human cancers. In this study, we applied a parallel-reaction monitoring (PRM)-based targeted proteomic method to assess kinome reprogramming during melanoma metast...

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Udgivet i:Sci Rep
Main Authors: Miao, Weili, Li, Lin, Liu, Xiaochuan, Qi, Tianyu F., Guo, Lei, Huang, Ming, Wang, Yinsheng
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7015909/
https://ncbi.nlm.nih.gov/pubmed/32051510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-59572-5
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