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Rhodopsin signaling mediates light-induced photoreceptor cell death in rd10 mice through a transducin-independent mechanism

Retinitis pigmentosa (RP) is a debilitating blinding disease affecting over 1.5 million people worldwide, but the mechanisms underlying this disease are not well understood. One of the common models used to study RP is the retinal degeneration-10 (rd10) mouse, which has a mutation in Phosphodiestera...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Sundar, Jesse C, Munezero, Daniella, Bryan-Haring, Caitlyn, Saravanan, Thamaraiselvi, Jacques, Angelica, Ramamurthy, Visvanathan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7015845/
https://ncbi.nlm.nih.gov/pubmed/31925423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddz299
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