Population pharmacokinetics and pharmacodynamics of dobutamine in neonates on the first days of life

AIMS: To describe the pharmacokinetics (PK) and concentration‐related effects of https://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=535 in critically ill neonates in the first days of life, using nonlinear mixed effects modelling. METHODS: Dosing, plasma concentration and haemody...

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Bibliographic Details
Published in:Br J Clin Pharmacol
Main Authors: Hallik, Maarja, Ilmoja, Mari‐Liis, Standing, Joseph F., Soeorg, Hiie, Jalas, Tiiu, Raidmäe, Maila, Uibo, Karin, Köbas, Kristel, Sõnajalg, Margit, Takkis, Kalev, Veigure, Rūta, Kipper, Karin, Starkopf, Joel, Metsvaht, Tuuli
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2020
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7015735/
https://ncbi.nlm.nih.gov/pubmed/31657867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.14146
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