B-Cell Clones as Early Markers for Chronic Lymphocytic Leukemia

BACKGROUND: Otherwise healthy persons with a small number of B-cell clones circulating in the peripheral blood have been designated as having monoclonal B-cell lymphocytosis (MBL). Hospital-based series indicate an excess risk of progression from MBL to chronic lymphocytic leukemia (CLL). In this pr...

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Veröffentlicht in:N Engl J Med
Hauptverfasser: Landgren, Ola, Albitar, Maher, Ma, Wanlong, Abbasi, Fatima, Hayes, Richard B., Ghia, Paolo, Marti, Gerald E., Caporaso, Neil E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7015348/
https://ncbi.nlm.nih.gov/pubmed/19213679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa0806122
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