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A quantitative account of mammalian rod phototransduction with PDE6 dimeric activation: responses to bright flashes

We develop an improved quantitative model of mammalian rod phototransduction, and we apply it to the prediction of responses to bright flashes of light. We take account of the recently characterized dimeric nature of PDE6 activation, where the configuration of primary importance has two transducin m...

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Detalhes bibliográficos
Publicado no:Open Biol
Main Authors: Lamb, Trevor D., Kraft, Timothy W.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7014685/
https://ncbi.nlm.nih.gov/pubmed/31910741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.190241
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