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Accumulation of DNA methylation alterations in paediatric glioma stem cells following fractionated dose irradiation

BACKGROUND: Radiation is an important therapeutic tool. However, radiotherapy has the potential to promote co-evolution of genetic and epigenetic changes that can drive tumour heterogeneity, formation of radioresistant cells and tumour relapse. There is a clinical need for a better understanding of...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Danielsson, Anna, Barreau, Kristell, Kling, Teresia, Tisell, Magnus, Carén, Helena
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7014676/
https://ncbi.nlm.nih.gov/pubmed/32046773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-020-0817-8
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