TFIIIC Binding to Alu Elements Controls Gene Expression via Chromatin Looping and Histone Acetylation

How repetitive elements, epigenetic modifications, and architectural proteins interact ensuring proper genome expression remains poorly understood. Here, we report regulatory mechanisms unveiling a central role of Alu elements (AEs) and RNA polymerase III transcription factor C (TFIIIC) in structura...

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Publicado en:Mol Cell
Main Authors: Ferrari, Roberto, de Llobet Cucalon, Lara Isabel, Di Vona, Chiara, Le Dilly, François, Vidal, Enrique, Lioutas, Antonios, Oliete, Javier Quilez, Jochem, Laura, Cutts, Erin, Dieci, Giorgio, Vannini, Alessandro, Teichmann, Martin, de la Luna, Susana, Beato, Miguel
Formato: Artigo
Idioma:Inglês
Publicado: Cell Press 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7014570/
https://ncbi.nlm.nih.gov/pubmed/31759822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.10.020
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