BCL-xL, a Mitochondrial Protein Involved in Successful Aging: From C. elegans to Human Centenarians

B-Cell Lymphoma-extra-large (BCL-xL) is involved in longevity and successful aging, which indicates a role for BCL-xL in cell survival pathway regulation. Beyond its well described role as an inhibitor of apoptosis by preventing cytochrome c release, BCL-xL has also been related, indirectly, to auto...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Borrás, Consuelo, Mas-Bargues, Cristina, Román-Domínguez, Aurora, Sanz-Ros, Jorge, Gimeno-Mallench, Lucia, Inglés, Marta, Gambini, Juan, Viña, José
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7014191/
https://ncbi.nlm.nih.gov/pubmed/31936510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21020418
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