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PIP(2) Mediated Inhibition of TREK Potassium Currents by Bradykinin in Mouse Sympathetic Neurons

Bradykinin (BK), a hormone inducing pain and inflammation, is known to inhibit potassium M-currents (I(M)) and to increase the excitability of the superior cervical ganglion (SCG) neurons by activating the Ca(2+)-calmodulin pathway. M-current is also reduced by muscarinic agonists through the deplet...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Rivas-Ramírez, Paula, Reboreda, Antonio, Rueda-Ruzafa, Lola, Herrera-Pérez, Salvador, Lamas, J. Antonio
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7014146/
https://ncbi.nlm.nih.gov/pubmed/31936257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21020389
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