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Partial Inhibition of RNA Polymerase I Promotes Animal Health and Longevity
Health and survival in old age can be improved by changes in gene expression. RNA polymerase (Pol) I is the essential, conserved enzyme whose task is to generate the pre-ribosomal RNA (rRNA). We find that reducing the levels of Pol I activity is sufficient to extend lifespan in the fruit fly. This e...
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| Publicado no: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7013379/ https://ncbi.nlm.nih.gov/pubmed/32049000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.01.017 |
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