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CD154 Induces Interleukin-6 Secretion by Kidney Tubular Epithelial Cells under Hypoxic Conditions: Inhibition by Chloroquine

Inflammation is a major contributor to tubular epithelium injury in kidney disorders, and the involvement of blood platelets in driving inflammation is increasingly stressed. CD154, the ligand of CD40, is one of the mediators supporting platelet proinflammatory properties. Although hypoxia is an ess...

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Bibliographic Details
Published in:Mediators Inflamm
Main Authors: Dewitte, Antoine, Villeneuve, Julien, Lepreux, Sébastien, Bouchecareilh, Marion, Gauthereau, Xavier, Rigothier, Claire, Combe, Christian, Ouattara, Alexandre, Ripoche, Jean
Format: Artigo
Language:Inglês
Published: Hindawi 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7013356/
https://ncbi.nlm.nih.gov/pubmed/32089648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/6357046
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