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Mycobacterial Trehalose 6,6′-Dimycolate–Induced M1-Type Inflammation

Murine models of Mycobacterium tuberculosis (Mtb) infection demonstrate progression of M1-like (proinflammatory) and M2-like (anti-inflammatory) macrophage morphology following primary granuloma formation. The Mtb cell wall cording factor, trehalose 6,6′-dimycolate (TDM), is a physiologically releva...

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Detalles Bibliográficos
Publicado en:Am J Pathol
Main Authors: Nguyen, Thao K.T., d'Aigle, John, Chinea, Luis, Niaz, Zainab, Hunter, Robert L., Hwang, Shen-An, Actor, Jeffrey K.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7013273/
https://ncbi.nlm.nih.gov/pubmed/31734231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2019.10.006
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