Mutation accumulation in cancer genes relates to nonoptimal outcome in chronic myeloid leukemia

Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm accounting for ∼15% of all leukemia. Progress of the disease from an indolent chronic phase to the more aggressive accelerated phase or blast phase (BP) occurs in a minority of cases and is associated with an accumulation of somatic mut...

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Udgivet i:Blood Adv
Main Authors: Adnan Awad, Shady, Kankainen, Matti, Ojala, Teija, Koskenvesa, Perttu, Eldfors, Samuli, Ghimire, Bishwa, Kumar, Ashwini, Kytölä, Soili, Kamel, Mahmoud M., Heckman, Caroline A., Porkka, Kimmo, Mustjoki, Satu
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2020
Fag:
Myeloid Neoplasia
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7013270/
https://ncbi.nlm.nih.gov/pubmed/32045476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000943
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