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Computational modeling of novel quinazoline derivatives as potent epidermal growth factor receptor inhibitors

QSAR modelling on Thirty (34) novel quinazoline derivatives (EGFR(WT) inhibitors) as non-small cell lung cancer (NSCLC) agents was performed to develop a model with good predictive power that can predict the activities of newly designed compounds that have not been synthesised. The EGFR(WT) inhibito...

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Publicado en:Heliyon
Autores principales: Ibrahim, Muhammad Tukur, Uzairu, Adamu, Uba, Sani, Shallangwa, Gideon Adamu
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7013192/
https://ncbi.nlm.nih.gov/pubmed/32072038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2020.e03289
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