Loss of cytoplasmic survivin expression is an independent predictor of poor prognosis in radically operated prostate cancer patients

Survivin is an inhibitor of apoptosis. Aberrant survivin expression occurs in malignant tumors and has often been linked to unfavorable patient outcome. Here we analyzed 12 432 prostate cancers by immunohistochemistry. Survivin immunostaining was regularly expressed at high levels in normal prostate...

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Bibliografische gegevens
Gepubliceerd in:Cancer Med
Hoofdauteurs: Büscheck, Franziska, Sulimankhil, Mariam, Melling, Nathaniel, Höflmayer, Doris, Hube‐Magg, Claudia, Simon, Ronald, Göbel, Cosima, Hinsch, Andrea, Weidemann, Sören, Izbicki, Jacob R., Jacobsen, Frank, Mandelkow, Tim, Blessin, Niclas C., Möller‐Koop, Christina, Lutz, Florian, Viehweger, Florian, Möller, Katharina, Sauter, Guido, Lennartz, Maximillian, Burandt, Eike, Lebok, Patrick, Minner, Sarah, Bonk, Sarah, Huland, Hartwig, Graefen, Markus, Schlomm, Thorsten, Fraune, Christoph
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2020
Onderwerpen:
Clinical Cancer Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7013067/
https://ncbi.nlm.nih.gov/pubmed/31893572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2773
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