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Effect of the novel histamine H(4) receptor antagonist SENS‐111 on spontaneous nystagmus in a rat model of acute unilateral vestibular loss

BACKGROUND AND PURPOSE: Histamine H(4) receptors are expressed in the peripheral vestibular system, and their selective inhibition improves vertigo symptoms in rats with unilateral vestibular lesions. The effects of SENS‐111, a selective oral H(4) receptor antagonist with high affinity to both anima...

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Publicado en:Br J Pharmacol
Autores principales: Petremann, Mathieu, Gueguen, Cindy, Delgado Betancourt, Viviana, Wersinger, Eric, Dyhrfjeld‐Johnsen, Jonas
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7012942/
https://ncbi.nlm.nih.gov/pubmed/31347148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14803
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