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Studies on citrullinated LL-37: detection in human airways, antibacterial effects and biophysical properties

Arginine residues of the antimicrobial peptide LL-37 can be citrullinated by peptidyl arginine deiminases, which reduce the positive charge of the peptide. Notably, citrullinated LL-37 has not yet been detected in human samples. In addition, functional and biophysical properties of citrullinated LL-...

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發表在:Sci Rep
Main Authors: Al-Adwani, Salma, Wallin, Cecilia, Balhuizen, Melanie D., Veldhuizen, Edwin J. A., Coorens, Maarten, Landreh, Michael, Végvári, Ákos, Smith, Margaretha E., Qvarfordt, Ingemar, Lindén, Anders, Gräslund, Astrid, Agerberth, Birgitta, Bergman, Peter
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7012854/
https://ncbi.nlm.nih.gov/pubmed/32047184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-59071-7
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